Heterogeneity in Statistical Genetics is popular PDF and ePub book, written by Derek Gordon in 2020-12-16, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Heterogeneity in Statistical Genetics can be Read Online from any device for your convenience.
Heterogeneity in Statistical Genetics Book PDF Summary
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon. In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association. We anticipate that this book will be useful to researchers who want to estimate heterogeneity in their data, develop or apply genetic association statistics where heterogeneity exists, and accurately evaluate statistical power and sample size for genetic association through the application of robust experimental design.
Detail Book of Heterogeneity in Statistical Genetics PDF
- Author : Derek Gordon
- Release : 16 December 2020
- Publisher : Springer Nature
- ISBN : 9783030611217
- Genre : Medical
- Total Page : 366 pages
- Language : English
- PDF File Size : 10,8 Mb
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