Environmental Factors Genes and the Development of Human Cancers is popular PDF and ePub book, written by Deodutta Roy in 2010-09-11, it is a fantastic choice for those who relish reading online the Medical genre. Let's immerse ourselves in this engaging Medical book by exploring the summary and details provided below. Remember, Environmental Factors Genes and the Development of Human Cancers can be Read Online from any device for your convenience.
Environmental Factors Genes and the Development of Human Cancers Book PDF Summary
Cancer is a complex disease. Only 5-10% of human cancers are hereditary in nature. Many of us think of environmental agents when we think of carcinogens. The environment includes all that surrounds us, and environmental influences include not only chemical, physical and biological toxicants, but also diet and lifestyle. In this broadest sense, the environment contributes substantially in the development of human cancer. This book will describe how environment contributes to malignant transformation leading to profound changes in the genetic and signaling networks that control the functioning of the cell. It will critically discuss the understanding of the effects of environment on the development, progression and metastasis of cancer with current knowledge of the signaling networks that support functioning of transformed human cells. Genes and environmental factors that influence the origins of cancer are not necessarily the same as those that contribute to its progression and metastasis. Susceptibility gene variants for each specific cancer are being identified with emerging evidence of gene–environment interaction. Gene-environment interactions will be discussed through each specific cancer-based approach to address the question of how genetic variations can influence susceptibility to the individual type of cancer. It will also highlight and summarize epigenetic changes that increase the risk for susceptibility to a particular type of cancer, particularly in the presence of specific environmental factors. Thus, this book will contain chapters from the world’s experts focused on the current evidences that support the role of environment in the cancer etiology and in the growth of malignant lesions, and discuss who may be susceptible to environmental influences.
Detail Book of Environmental Factors Genes and the Development of Human Cancers PDF
- Author : Deodutta Roy
- Release : 11 September 2010
- Publisher : Springer Science & Business Media
- ISBN : 9781441967527
- Genre : Medical
- Total Page : 521 pages
- Language : English
- PDF File Size : 11,6 Mb
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